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KMID : 0366219840190010021
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Korean Journal of Hematology
1984 Volume.19 No. 1 p.21 ~ p.28
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A Clinical Study on Cardiac Heinolytic Anemia
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한지숙/Jee Sook Hahn
박필원/윤진우/고윤웅/심원흠/이웅구/Pil Won Park/Jhin Woo Yoon/Yun Woog Ko/Won Heum Shim/Woong-Ku Lee
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Abstract
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Heimolytic anemia has occasionally been associatd with valvular heart disease and
more frequently with malfunctioning cardiac valve prostheses.
While replacentent of diseased cardiac valves with artificial prostheses is steadily
increasing in numbers in Korea, there has been no report of studies on the mechanical
hemolysis associated with malfunction of the native or prosthetic cardiac values in this
country.
This study was to investigate the evidence of hemolysis/anemia in 23 Patients with
valvular heart disease and four with congenital heart disease seen during January
Novernber, 1983, and the results obtained were as follows:
1. There were 23 cases of valvular heart disease, and 16 of 23 had mitral valve
disease and 4 of 23 had aortic valve involvement while three had disease in both of the
valves. Eight of the 23 patients were seen in the postoperative course following
prosthetic valve implantation. Four patients with congenital heart disease were also
evaluates in the postoperative hospital course.
2. The cardiac hemolytic anemia was considered present in 1 of 15(4.3%) patients
with valvular disease without replacement surgery, 4 of 8(50.0%) patients with prosthetic
implantation, and 1 of 4(25.0%) cases of congenital heart disease seen in the
postoperative period. Cardiac hemolysis without anemia was present in one patient with
valvular heart disease without surgery.
These findings indicate that mechanical hemolytic anemia occurs not「infrequently
among the patients with valvular heart disease especially following replacement of the
diseased valves with artificial prostheses.
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KEYWORD
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